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Sources:

Found: Mouse Circadian Rhythm Gene

Investigators have found the first gene involved in the mammalian biological clock, the internal timepiece that regulates activities ranging from sleeping to eating.

Sources:

Steven M. Reppert
Laboratory of Developmental Chronobiology
Massachusetts General Hospital
Boston, MA 02114

Joseph S. Takahashi
National Science Foundation Center for Biological Timing
Northwestern University
Department of Neurobiology and Physiology
Evanston, Ill 60208


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Computer triumphs over human champion

Deep Blue defeated world chess champion Garry Kasaprov in a six-game match.

Sources:

Chung-Jen Tan
IBM Thomas J. Watson Research Center
Yorktown Heights, NY 10598

Garry Kasparov
Website: http://www.club-kasparov.com/


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Can preventive mastectomies prolong lives?

A computer model suggests that preventive mastectomies for some women carrying a breast cancer gene may add to their life expectancy.


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Health may succumb to grief reaction

A particularly severe form of bereavement known as traumatic grief appears to increase the likelihood of physical and mental problems as many as two years after a spouse's death.

Sources:

Holly G. Prigerson
Connecticut Mental Health Center
Yale University School of Medicine
34 Park Street
New Haven, CT 06519

Sidney Zisook
Department of Psychiatry
University of California San Diego School of Medicine
9500 Gilman Drive
La Jolla, CA 92093


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Grim prospects for flood-ravaged R&D

Many researchers in Grand Forks, N.D., are tallying staggering -- and, in some cases, long-term -- losses.

Sources:

Albert J. Fivizzani
Biology Department
University of North Dakota
P.O. Box 9109
Grand Forks, ND 58202

Gerald H. Groenewold
Energy and Environmental Research Center
University of North Dakota
P.O. Box 8103
University Station
Grand Forks, ND 58202
Ph: 701-777-5131

Barry Milavetz
Department of Biochemistry and Molecular Biology
University of North Dakota Medical School
P.O. Box 9037
Grand Forks, ND 58202

Forrest Nielsen
Agricultural Research Service
Grand Forks Human Nutrition Research Center
P.O. Box 9034
University Station
Grand Forks, ND 58201
E-mail: fnielsen@sage.und.nodak.edu
Website: http://www.npa.ars.usda.gov/north.htm

Robert C. Nordlie
Department of Biochemistry and Molecular Biology
University of North Dakota Medical School
P.O. Box 9037
Grand Forks, ND 58202

Fargo Flood Homepage
North Dakota State University
Website: http://www.ndsu.nodak.edu/fargoflood/

University of North Dakota Food-Related Information
Website: http://www.und.nodak.edu/flood/flood.html


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Checking out Hubble's new eyes

Two new instruments installed aboard the Hubble Space Telescope last February are proving their mettle.

Sources:

Bruce E. Woodgate
NASA Goddard Space Flight Center
Greenbelt, MD 20771


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Impurities give crystals that special glow

Crystal structure and impurities may explain why some materials give off light when fractured.

Sources:

Bart E. Kahr
Department of Chemistry
University of Washington
Box 351700
Seattle, WA 98195-1700
E-mail: kahr@chem.washington.edu

Arnold L. Rheingold
Department of Chemistry
University of Delaware
Newark, DE 19716
E-mail: arnrhein@udel.edu

Linda M. Sweeting
Department of Chemistry
Towson State University
Towson, MD 21252-7097
E-mail: sweeting@towson.edu
Website: http://www.towson.edu/~sweeting/


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A price tag on the planet's ecosystems

Sources:

Robert Costanza
Institute for Ecological Economics
University of Maryland
Box 38
Solomons, MD 20688
Website: http://kabir.cbl.cees.edu/ISEE/ISEEhome.html

Lawrence H. Goulder
Department of Economics and Institute for International Studies
Stanford University
Stanford, CA 94305

Stuart L. Pimm
Department of Evolutionary Ecology and Evolutionary Biology
University of Tennessee
Knoxville, TN 37996


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Research Notes:

Astronomy

More planets

Astronomers have deduced the presence of additional planets orbiting nearby stars.

Sources:

Robert W. Noyes
Smithsonian Astrophysical Observatory
60 Garden Street
Cambridge, MA 02138

John Mattox
Boston University
725 Commonwealth Avenue
Boston, MA 02215


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Gamma-ray burst mystery continues

A new interpretation of a recent pair of Hubble Space Telescope images has revived controversy about the origin of a gamma-ray burst detected in late February.

Sources:

Kailash C. Sahu
Space Telescope Science Institute
3700 San Martin Drive
Baltimore, MD 21218


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Biology

What good is the cystic fibrosis gene?

Researchers suggest cystic fibrosis is widespread because the genetic mutations that produce the disease can also offer protection against typhoid fever.

Sources:

Gerald Pier
Brigham and Women's Hospital
Harvard Medical School
Channing Laboratory
181 Longwood Avenue
Boston, MA 02115-5899


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Bacteria that don't say no to cocaine

An enzyme isolated from bacteria that feed on cocaine may one day serve as a simple sensor of the drug.

Sources:

Matthew Bresler
Institute of Biotechnology
University of Cambridge
Tennis Court Road
Cambridge CB2 1QT
United Kingdom


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Archeology

Urban planning in ancient Near East

Excavations at a 4,000-year-old city in Turkey have uncovered a planned community of dwellings that bears a strong resemblance to modern urban settings.

Sources:

Guillermo Algaze
Department of Anthropology
University of California
9500 Gilman Drive
La Jolla, CA 92093-0938

Timothy Matney
Department of Anthropology
Whitman College
345 Boyer Avenue
Walla Walla, WA 99362


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Biomedicine

Death zone for stroke

A 153-county area in the southeastern United States has a particularly high incidence of stroke.

Sources:

George Howard
Department of Public Health Sciences
Bowman Gray School of Medicine
Winston-Salem, NC 27157-1063


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Vaccine shields chimps from AIDS

A DNA vaccine protects chimps from HIV infection.

Sources:

David B. Weiner
Department of Pathology
University of Pennsylvania
505 Stellar-Chance Building
422 Curie Boulevard
Philadelphia, PA 19104


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Articles:

Those Old Dioxin Blues

Some small fry are exquisitely sensitive models of dioxin vulnerability

In studying the hitherto largely unrecognized toxicity of dioxinlike compounds in fish, scientists stumbled onto a new model for probing the pollutants' effects in higher animals.

Sources:

Philip M. Cook
National Health and Environmental Effects Research Laboratory
Mid-Continent Ecology Division
U.S. Environmental Protection Agency
6201 Congdon Boulevard
Duluth, MN 55804

Marc Gaden
Great Lakes Fishery Commission
2100 Commonwealth Boulevard, Suite 209
Ann Arbor, MI 48105

John P. Giesy
Department of Fisheries and Wildlife
Institute for Environmental Toxicology
Pesticide Resesarch Center
Michigan State University
East Lansing, MI 48824-1222
E-mail: jgiesy@aol.com

Michael Gilbertson
International Joint Commission
P.O. Box 32869
Detroit, MI 48232

Mark E. Hahn
Biology Department, MS-32
Woods Hole Oceanographic Institution
Woods Hole, MA 02543-1049

Michael Mac
United States Geological Survey National Center
M.S. 301
12201 Sunrise Valley Drive
Reston, VA 20192

Richard E. Peterson
School of Pharmacy
5293 Chamberlin Hall
425 N. Charter Street
University of Wisconsin-Madison
Madison, WI 53706

Clifford P. Schneider
New York State Department of Environmental Conservation
Cape Vincent Fisheries Station
P.O. Box 292
Cape Vincent, NY 13618

Mark R. Servos
Environment Canada
National Water Research Institute
867 Lakeshore Road
Burlington, ON L7R 4A6
Canada

John J. Stegeman
Biology Department, M.S. 32
Woods Hole Oceanographic Institution
Woods Hole, MA 02543

Donald E. Tillitt
Midwest Science Center
U.S. Geological Survey
Biological Resource Division
4200 New Haven Road
Columbia, MO 65201


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Proliferation of Pills

Antibiotics don't fight many infections well, yet doctors continue to prescribe them

As resistance to antibiotics grows, doctors scramble for new ways to deal with tougher bugs.

Sources:

F.L. van Buchem
St. Elisabeth Hospital
Tilburg
P.O. Box 90151
5000 LC Tilburg
The Netherlands

Jack Gwaltney
University of Virginia Health Science Center
Box 429, McKim Hall
Charlottesville, VA 22908

Stuart Levy
Tufts University
419 Boston Avenue
Medford, MA 02150

Richard Lockey
University of South Florida
4202 East Fowler Avenue
ADM 264
Tampa, FL 33620-6300

John E. McGowan
Rollins School of Public Health
Emory University School of Medicine
Epidemiology Department (442 GCR)
Emory University
Atlanta, GA 30322

Benjamin Schwartz
National Center for Infectious Diseases
Centers for Disease Control and Prevention
1600 Clifton Road, N.E., MS-C-23
Atlanta, GA 30333


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Table of Contents - 5/17/97


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