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DNA computing tricks add up to progress

By biochemically manipulating DNA strands attached to a gold surface, researchers have performed two more DNA computing operations similar to those executed by a conventional computer.

 

References:

Frutos, A.G., L.M. Smith, and R.M. Corn. 1998. Enzymatic ligation reactions of DNA "words" on surfaces for DNA computing. Journal of the American Chemical Society 120(Oct. 14).

 

Further Readings:

Frutos, A.G., et al. 1997. Demonstration of a word design strategy for DNA computing on surfaces. Nucleic Acids Research 25:4748.

Peterson, I. 1996. Computing with DNA. Science News 150(July 13):26.

______. 1996. Test-tube stickers for DNA-based computers. Science News 149(June 22):391.

______. 1994. Molecular computing in a DNA soup. Science News 146(Nov. 12):308.

Smith, L.M., et al. 1998. A surface-based approach to DNA computation. Journal of Computational Biology 5(Nov. 2):255.

Sources:

Robert M. Corn
University of Wisconsin, Madison
Department of Chemistry
Madison, WI 53706

John H. Reif
Duke University
Department of Computer Science
Durham, NC 27707

From Science News, Vol. 154, No. 17, October 24, 1998, p. 263.
Copyright Ó 1998 by Science Service.

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