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Blood, semen harbor distinct HIV mutations

Different, drug-resistant populations of HIV can arise in different locations in the same infected man.

 

References:

Byrn, R.A. . . . A.A. Kiessling. 1997. HIV-1 in semen: An isolated virus reservoir. Lancet 350(Oct. 18):1141.

Eron, J.J. . . . M.S. Cohen. 1998. Resistance of HIV-1 to antiretroviral agents in blood and seminal plasma: Implications for transmission. AIDS 12(Oct. 22).

 

Further Readings:

Cohen, M.S., et al. 1997. Reduction of concentration of HIV-1 in semen after treatment of urethritis: Implications for prevention of sexual transmission of HIV-1. Lancet 349(June 28):1868.

Delwart, E.L., et al. 1998. Human immunodeficiency virus Type 1 populations in blood and semen. Journal of Virology 72(January):617.

Kiessling, A.A. 1994. Human immunodeficiency virus in semen. Current Opinion in Urology 4:60.

 

Sources:

Myron S. Cohen
University of North Carolina, Chapel Hill
Department of Medicine
CB 7030, 547 Burnett-Womack Building
Chapel Hill, NC 27599-7030

Anthony S. Fauci
National Institutes of Health
National Institute of Allergy and Infectious Diseases
31 Center Drive, Building 31
Room 7A03
Bethesda, MD 20892-2520

Ann A. Kiessling
Harvard Medical School
Beth Israel Deaconess Medical Center
4 Blackfan Circle
Boston, MA 02115

From Science News, Vol. 154, No. 18, October 31, 1998, p. 279.
Copyright Ó 1998 by Science Service.

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