Science News Online (11/28/98): References for Gel swells during high-sugar spells

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Gel swells during high-sugar spells

A soft gel that shrinks and swells in response to changing sugar concentrations could offer a new way to deliver insulin to people with diabetes.

References:

Kataoka, K., et al. 1998. Totally synthetic polymer gels responding to external glucose concentration: Their preparation and application to on-off regulation of insulin release. Journal of the American Chemical Society. Available at http://pubs.acs.org/subscribe/journals/jacsat/browse_asap.html.

Further Readings:

Lipkin, R. 1995. Tiny microspheres release drugs slowly. Science News 147(April 29):262.

Raloff, J. 1997. New glucose test on the way for diabetes. Science News 151(March 29):190.

Smaglik, P. 1997. Swapping insulin syringes for tiny beads. Science News 151(March 29):189.

Wu, C. 1997. Liquid-to-gel polymer delivers drugs. Science News 152(Sept. 13):170.

______. 1996. Gels can give drugs a timely release. Science News 150(Sept. 7):159.

Sources:

Kazunori Kataoka
University of Tokyo
7-3-1 Hongo, Bunko-ku
Tokyo 113-8656
Japan

Sung Wan Kim
University of Utah
Department of Pharmaceutics and Pharmaceutical Chemistry
301 Skaggs Hall
Salt Lake City, UT 84112

From Science News, Vol. 154, No. 22, November 28, 1998, p. 340. Copyright Ó 1998 by Science Service.

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