Gene-therapy advances go to the heart
Gene therapy helps arteries to regrow in heart tissue and may limit clogging of vessels used in bypass surgery.
References:
Mann, M.J., et al. 1998. The PREVENT trial of genetic engineering to prevent blockages after bypass operations, and gene therapy and TMR: an animal study. Meeting of the American Heart Association. November. Dallas.
Vale, P.R. . . . J.M. Isner. 1998. Gene therapy for myocardial angiogenesis. Meeting of the American Heart Association. November. Dallas.
Further Readings:
Fackelmann, K.A. 1994. Growth factors boost heart’s blood flow. Science News 145(Jan. 29):71.
Isner, J.M., and L.J. Feldman. 1994. Gene therapy for arterial disease. Lancet 344(Dec. 17):1653.
McCarthy, M. 1997. Vascular gene therapy studies show promise. Lancet 350(Nov. 15):1451.
Mulligan, R.C. 1993. The basic science of gene therapy. Science 260:926.
Ohno, T., et al. 1994. Gene therapy for vascular smooth muscle cell proliferation after arterial injury. Science 265:781.
Sources:
Jeffrey M. Isner
St. Elizabeth’s Medical Center
736 Cambridge Street
Boston, MA 02135Michael J. Mann
Brigham and Women’s Hospital
75 Francis Street
Boston, MA 02115From Science News, Vol. 154, No. 22, November 28, 1998, p. 346. Copyright Ó 1998 by Science Service.
11/28/98
copyright 1998 ScienceService
