Shining light on a clocks proteins
Light-detecting proteins called cryptochromes play a role in plant and animal biological clocks.
References:
Emory, P. . . . J.C. Hall, and M. Rosbash. 1998. CRY, a Drosophila clock and light-regulated cryptochrome, is a major contributor to circadian rhythm resetting and photosensitivity. Cell 95(Nov. 25):669.
Somers, D.E., P.F. Devlin, and S.A. Kay. 1998. Phytochromes and cryptochromes in the entrainment of the Arabidopsis circadian clock. Science 282(Nov. 20):1488.
Stanewsky, R. . . . M. Rosbash, and J.C. Hall. 1998. The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila. Cell 95(Nov. 25):681.
Thresher, R.J. . . . A. Sancar. 1998. Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses. Science 282(Nov. 20):1490.
Further Readings:
Travis, J. 1998. Timely surprises. Science News 154(July 11):24.
Sources:
Jeffrey C. Hall
Brandeis University
Department of Biology
National Science Foundation Center for Biological Timing
Waltham, MA 02454Michael Rosbash
Brandeis University
Department of Biology
National Science Foundation Center for Biological Timing
Howard Hughes Medical Institute
Waltham, MA 02454Aziz Sancar
University of North Carolina
School of Medicine
Department of Biochemistry and Biophysics
Chapel Hill, NC 27599David E. Somers
Scripps Research Institute
Department of Cell Biology
National Science Foundation Center for Biological Timing
10550 North Torrey Pines Road
La Jolla, CA 92307
From Science News, Vol. 154, No. 24, December 12,
1998, p. 379.
Copyright Ó 1998 by Science Service.
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