Science News Online (12/19/98): References for New Gene Therapy Fights Frailty

References & Sources - December 19 & 26, 1998

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Gene therapy in animals successfully halted age-related muscle loss, pointing a way to a treatment for people.

References:

Barton-Davis, E.R. . . . N. Rosenthal, and H.L. Sweeney. 1998. Viral mediated expression of IGF-I keeps muscles young and strong in old mice. Meeting of the American Society for Cell Biology. December. San Francisco.

______. 1998. Viral mediated expression of IGF-I blocks the aging-related loss of skeletal muscle function. Proceedings of the National Academy of Sciences 95(Dec. 22).

Further Readings:

Raloff, J. 1996. Vanishing flesh. Science News 150(Aug. 10):90.

Sources:

Elizabeth R. Barton-Davis
University of Pennsylvania School of Medicine
A-700 Richards Building
37th & Hamilton Walk
Philadelphia, PA 19104-6085

Leon I. Charash
400 South Olyster Bay Road
Hicksville, NY 11801

Anna M. McCormick
National Institute on Aging
Biology of Aging Program
Gateway Building, Suite 2C231
Bethesda, MD 20892

Muscular Dystrophy Association
3300 East Sunrise Drive
Tucson, AZ 85718

Charlotte Peterson
University of Arkansas
VA Hospital, Res. 151
4300 West 7th Street
Little Rock, AR 72205

Nadia Rosenthal
Massachusetts General Hospital-East
Cardiovascular Research Center
149 13th Street
Charlestown, MA 02129

H. Lee Sweeney
University of Pennsylvania School of Medicine
Department of Physiology
A-700 Richards Building
37th & Hamilton Walk
Philadelphia, PA 19104-6085

From Science News, Vol. 154, No. 25 & 26, December 19 & 26, 1998, p. 388. Copyright Ó 1998 by Science Service.

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