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Diabetic Pregnancy Risk Starts Early

The risks faced by fetuses in diabetic mothers may stem from high sugar concentrations, causing excess cell death soon after conception.

 

References:

Moley, K.H., et al. 1998. Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways. Nature Medicine 4(December):1421.

 

Further Readings:

1996. Honourable death. Economist 339(May 4):83.

Centofanti, M. 1995. Diabetes complications: More than sugar? Science News 148(Dec. 23&30):421.

Fishman, R.H.B. 1995. Debate over diabetes-in-pregnancy study. Lancet 345(April 8):915.

Peters, R.K., et al. 1996. Long-term diabetogenic effect of single pregnancy in women with previous gestational diabetes mellitus. Lancet 347(Jan. 27):227.

Reece, A., and D.R. Coustan. 1996. Diabetes Mellitus in Pregnancy. New York: Churchill Livingstone.

Schwartz, S., et al. 1998. Effect of troglitazone in insulin-treated patients with Type II diabetes mellitus. New England Journal of Medicine 338(March 26):861.

Travis, J. 1997. Diabetes results from suicidal cells. Science News 151(Feb. 1):72.

Sources:

David R. Hadden
Royal Victoria Hospital
BT126BA
Belfast, Northern Ireland
United Kingdom

Kelle H. Moley
Washington University
School of Medicine
2nd Floor Maternity Hospital
4911 Barnes Hospital Plaza
St. Louis, MO 63110

From Science News, Vol. 154, No. 23, December 5, 1998, p. 356. Copyright Ó 1998 by Science Service.

 

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