References & Sources - July 25, 1998 Lyme Vaccine Proves Highly Effective
Two large studies find that a vaccine against Lyme disease vaccine can protect people against the tickborne disease, particularly after a booster shot is given.
References:
Sigal, L.H., et al. 1998. A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. New England Journal of Medicine 339(July 23):216.
Steere, A.C., et al. 1998. Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. New England Journal of Medicine 339(July 23):209.
Further Readings:
Barthold, S.W. 1996. Globalisation of Lyme Borreliosis. Lancet 348(Dec. 14):1603.
Burgdorfer W., et al. 1982. Lyme disease — a tick-borne spirochetosis? Science 216:1317.
Pfister, H., B. Wilske, and K. Weber. 1994. Lyme Borreliosis: Basic science and clinical aspects. Lancet 343(April 23):1013.
Steere, A.C., et al. 1983. The spirochetal etiology of Lyme disease. New England Journal of Medicine 308:733.
Steigbigel, R.T., and J.L. Benach. 1998. Immunization against Lyme disease — an important first step. New England Journal of Medicine 339(July 23):263.
Sources:
Leonard H. Sigal
Robert Wood Johnson Medical School
1 Robert Wood Johnson Place
MEB 484
New Brunswick, NJ 08903-0019
Allen C. Steere
Tufts University School of Medicine New England Medical Center Bo
406, 750 Washington Street
Boston, MA 02111
Philip J. Wand
University of Wisconsin, Madison
State Laboratory of Hygiene
465 Henry Mall
Madison, WI 53706
7/25/98
copyright 1998 ScienceService
