Possible Alzheimers gene stirs conflict
Researchers disagree on whether a specific gene on chromosome 12 influences a person's chance of getting Alzheimers disease late in life.
References:
1998. APOE genotype predicts when not whether one is predisposed to develop Alzheimer disease. Nature Genetics 19(August):321.
Alzheimer Association. Sixth International Conference on Alzheimer's Disease and Related Disorders. July. Amsterdam, Netherlands.
Blacker, D. . . . R.E. Tanzi. 1998. Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nature Genetics 19(August):357.
Further Readings:
Price, D.L., S.S. Sisodia, and D.R. Borchelt. 1998. Alzheimer disease when and why? Nature Genetics 19(August):314.
Sources:
Margaret A. Pericak-Vance
Duke University Medical Center
Department of Medicine
P.O. Box 3445
Durham, NC 27710
Peter H. St. George-Hsylop
University of Toronto
Tanz Neuroscience Building
6 Queen's Park Crescent West
Toronto, Ontario M5S 1A8
CanadaRudolph E. Tanzi
Massachusetts General Hospital
Department of Neurology
Genetics and Aging Unit
Boston, MA 02114
E-mail: tanzi@helix.mgh.harvard.edu
7/25/98
copyright 1998 ScienceService