References & Sources - August 29, 1998 Alzheimer's link to eye disease seen
A mutant variety of the gene that codes for apolipoprotein puts people at lower risk of developing Alzheimer’s disease but at higher peril of getting macular degeneration.
References:
Klaver, C.C.W., et al. 1998. Genetic association of apolipoprotein E with age-related macular degeneration. American Journal of Human Genetics 63(July):200.
Further Readings:
Allikmets, R., et al. 1997. Mutation of the stargardt disease gene (ABCR) in age-related macular degeneration. Science 277(Sept. 19):1805.
Bower, B. 1996. Alzheimer’s disease takes a curious turn. Science News 150(Oct. 12):229.
Pennisi, E. 1997. Gene found for the fading eyesight of old age. Science 277(Sept. 19):1765.
Seppa. N. 1997. New treatments for macular degeneration. Science News 152(Sept. 27):198.
Sternberg, S. 1996. Smokers risk vision loss in twilight years. Science News 150(Oct. 12):231.
Additional information about macular degeneration can be found at: http://www.retinavitreous.com/diseases/degen.htm and http://www.eyesight.org/.
Sources:
Caroline C.W. Klaver
Erasmus University Medical School
Departments of Epidemiology, Biostatistics, and Ophthalmology
Garenmarkt
1 2311 PG
Leiden
NetherlandsRichard A. Lewis
Baylor College of Medicine
Department of Opthalmology
One Baylor Plaza, NC-206
Houston, TX 77030
8/29/98
copyright 1998 ScienceService
