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Cancer drug reveals unexpected partner

The drug taxol may make tumor cells die by binding to a protein called Bcl-2, a more direct anticancer effect than anticipated.

References:

Rodi, D.J. . . . L. Makowski. 1998. Screening of a library of phage-displayed peptides identifies human Bcl-2 as a taxol-binding protein. Journal of Molecular Biology(Jan. 8).

Sources:

Lee Makowski
National Science Foundation
4201 Wilson Boulevard
Arlington, VA 22230

Diane J. Rodi
Florida State University
Institute of Molecular Biophysics
Tallahassee, FL 32306

From Science News, Vol. 155, No. 4, January 23, 1999, p. 56. Copyright © 1999, Science Service.

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