Nicotine addiction curbed by new drug
An anti-epilepsy drug called gamma vinyl-GABA blocks the craving for nicotine in rats addicted to nicotine
.References:
Dewey, S.L., et al. 1999. A pharmacologic strategy for the treatment of nicotine addiction. Synapse 31(January):76.
Further Readings:
Chesselet, M-F. 1984. Presynaptic regulation of neurotransmitter release in the brain: Facts and hypothesis. Neuroscience 12:347.
Corrigall, W.A., and K.M. Coan. 1991. Selective dopamine antagonists reduce nicotine self-administration. Psychopharmacology 104:171.
Sources:
Stephen L. Dewey
Brookhaven National Laboratory
Chemistry Department
Upton, NY 11973
From Science News, Vol. 155, No. 1, January 2, 1999, p. 11. Copyright © 1999 by Science Service.
copyright 1999 ScienceService