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AZT shows no ill effects on babies
Exposure to the anti-HIV drug AZT shows few long-term effects in babies not infected with HIV.
Culnane, M., et al. 1999. Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Journal of the American Medical Association 281(Jan. 13):151.
Ayers, K.M., et al. 1996. Nonclinical toxicology studies with zidovudine: Genetic toxicity and carcinogenicity bioassays in mice and rats. Fundamental and Applied Toxicology 32:148.
Connor, E.M., et al. 1994. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. New England Journal of Medicine 331:1173.
National Institute of Health
National Institute of Allergy and Infectious Diseases
Pediatric Medicine Branch
Division of AIDS
9000 Rockville Pike
Bethesda, MD 20892-7620
From Science News, Vol. 155, No. 6, February 6, 1999, p. 95. Copyright © 1999, Science Service.