Well-Done
Research
New recipes for making seriously browned meats less of a cancer
risk
Adding fruit to meat, using certain
marinades, or drinking beer to accompany a meat dish show promise in
quashing the carcinogens that can form in meats as they cook.
References:
Arimoto-Kobayashi, S., et al. 1999. Inhibitory effects of
beer and other alcoholic beverages on mutagenesis and DNA adduct formation
induced by several carcinogens. Journal of Agricultural and Food
Chemistry 47(January):221.
Britt, C. . . . J.I. Gray, et al. 1998. Influence of cherry
tissue on lipid oxidation and heterocyclic aromatic amine formation
on ground beef patties. Journal of Agricultural and Food Chemistry
46(December):4891.
Mauthe, R.J. . . . and K.W. Turteltaub. 1999. Comparison of DNA-adduct
and tissue-available dose levels of MeIQx in human and rodent colon
following administration of a very low dose. International Journal
of Cancer 80(Feb. 9):539.
Further Readings:
Augustsson, K., et al. 1999. Dietary heterocyclic amines and
cancer of the colon, rectum, bladder, and kidney: A population-based
study. Lancet 353(Feb. 27):703.
Dingley, K.H. . . . J.S. Felton, and K.T. Turteltaub. In press. Adduct
formation in the colon and blood of humans following exposure to a
dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
(PhIP). Cancer Epidemiology, Biomarkers and Prevention.
Dingley, K.H. . . . and K.W. Turteltaub. 1998. Covalent binding of
2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline to albumin and
hemoglobin at environmentally relevant doses. Drug Metabolism and
Disposition 26:825.
Forman, D. 1999. Meat and cancer: A relation in search of a mechanism.
Lancet 353(Feb. 27):686.
Raloff, J. 1999. Arthritis care: Beyond tea and sympathy. Science
News 155(April 17):247.
______. 1998. Very hot grills
may inflame cancer risks. Science News 154(Nov. 28):341.
______. 1996. Another meaty link to cancer. Science News 149(June
8):365.
______. 1994. Meaty carcinogens: A risk to the cook? Science News
146(Aug. 13):103.
______. 1994. Not so hot hot dogs? Science News 145(April
23):264.
______. 1994. How cooked meat may inflame the heart. Science News
145(March 12):165.
______. 1994. Sorting out cancer IQs in browned meat. Science
News 145(Jan. 8):22.
______. 1992. Cancer-fighting food additives. Science News
141(Feb. 15):104.
______. 1986. Cholesterol/oxides debate isn't over. Science News
130(Dec. 13):377.
______. 1985. Oxidized lipids: A key to heart disease? Science
News 127(May 4):278.
______. 1985. Cottonseed flour retards rancidity. Science News
127(Feb. 9):88.
Sources:
Mary Adolf
National Cattlemen's Beef Association
444 North Michigan Avenue
Chicago, IL 60611
Jane Baker
Cherry Marketing Institute
P.O. Box 30285
Lansing, MI 48909-7785
Web site: http://www.cherrymkt.org
Karen Dingley
Lawrence Livermore National Laboratory
Biology and Biotechnology Research Program
P.O. Box 808, L-452
Livermore, CA 94551-9900
Sara Fein
FDA HFS-727
200 C. Street, S.W.
Washington, DC 20204
Pratibha Nerurkar
Cancer Research Center of Hawaii
Etiology Program
1236 Lauhala Street Room 506
Honolulu, HI 96813
Raymond M. Pleva
Ray Pleva's Products, Inc.
9101 South Lake Shore Drive
Cedar, MI 49621
Katherine Ralston
Economic Research Service, USDA
Food and Rural Economics Division
1800 M Street, N.W.
Washington, DC 20036-5831
Elizabeth Snyderwine
National Cancer Institute
Laboratory of Experimental Carcinogenesis
Building 37, Room 3C-28
Bethesda, MD 20892-4255
Kenneth W. Turteltaub
Lawrence Livermore National Laboratory
Biology and Biotechnology Research Program, L-452
Livermore, CA 94550
John Weisburger
American Health Foundation
Director Emeritus
One Dana Road
Valhalla, NY 10595
From Science
News, Vol. 155, No. 17, April 24,
1999, p. 264. Copyright © 1999, Science Service.
