Closing the loop on the end of a chromosome

The tips of chromosomes end in protective loops of DNA, heretofore unsuspected.

References:

Greider, C.W. 1999. Telomeres do D-loop-T-loop. Cell 97(May 14):419.

Griffith, J.D. . . . and T. de Lange. 1999. Mammalian telomeres end in a large duplex loop. Cell 97(May 14):503.

Further Readings:

Travis, J. 1995. End games. Science News 148(Nov. 25):362.

Sources:

Titia de Lange
Rockefeller University
New York, NY 10021

Jack D. Griffith
University of North Carolina at Chapel Hill
Lineberger Comprehensive Cancer Center
Curriculum in Genetics and Molecular Biology
Chapel Hill, NC 27599-7295

From Science News, Vol. 155, No. 21, May 22, 1999, p. 326. Copyright © 1999, Science Service.

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