Altered buckyballs
go straight to bone
Molecules of carbon known as buckyballs,
being designed to encapsulate and deliver drugs, can directly target
diseased tissues.
References:
Cagle, D.W. . . . and L.J. Wilson. 1999. In vivo studies of
fullerene-based materials using endohedral metallofullerene radiotracers.
Proceedings of the National Academy of Sciences 96(April 27):5182.
Gonzalez, K.A., L.J. Wilson, W. Wu, and G.H. Nancollas. 1999. Tissue
targeting of fullerene-based materials: Vectoring C60 to bone. Meeting
of the Electrochemical Society. May. Seattle.
Further Readings:
1990. Making scads of molecular soccer balls. Science News
138(Oct.13):238.
Amato, I. 1990. Buckyballs get their first major physical. Science
News 138(Dec. 8):357.
Curl, R.F., and R.E. Smalley. 1991. Fullerenes. Scientific American
265(October):54.
Peterson, I. 1985. Molecular carbon: Playing 'buckyball.' Science
News 128(Nov. 23):325.
Wu, C. 1997. New drugs zap cancer
cells with radiation. Science News 151(Feb. 22):117.
______. 1996. Buckyballs bounce into Nobel History. Science News
150(Oct. 19):247.
Sources:
Kelly A. Gonzalez
Rice University
Department of Chemistry
Center for Nanoscale Science and Technology
Mailstop Code 60
P.O. Box 1892
Houston, TX 77251-1892
Lon J. Wilson
Rice University
Department of Chemistry
Center for Nanoscale Science and Technology
Mailstop Code 60
P.O. Box 1892
Houston, TX 77251-1892
Stephen R. Wilson
New York University
Department of Chemistry
100 Washington Square North
New York, NY 10003
From Science
News, Vol. 155, No. 19, May 8, 1999, p. 292.
Copyright © 1999, Science Service.