Diuretic may treat autism, study in rodents suggests

Drug that affects brain chloride levels staves off symptoms in mice and rats

By Laura Sanders, 13:22 PM February 6, 2014

Curbing chloride in nerve cells could combat symptoms of autism, a study of rats and mice suggests. The results may explain why a small group of children with autism seemed to improve after taking the common diuretic bumetanide in an earlier study.

The new details of how bumetanide works, published in the Feb. 7 Science, provide important clues about how autism spectrum disorders arise in a developing brain, says Susan Connors, an autism specialist at Massachusetts General Hospital for Childre...

Source URL: https://www.sciencenews.org/article/diuretic-may-treat-autism-study-rodents-suggests?mode=magazine&context=188098