References & Sources  -  October 10, 1998

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RNA folding process reveals a new twist

RNA molecules can rearrange their internal structures even as they fold into their final, three-dimensional shapes.

 

References:

Wu, M., and I. Tinoco, Jr. 1998. RNA folding causes secondary structure rearrangement. Proceedings of the National Academy of Sciences 95(Sept. 29):11555.

 

Further Readings:

Bartel, D. 1995. Artificial RNA enzymes: Big and fast. Science News 148(July 22):53.

Cate, J.H., et al. 1996. Crystal structure of a Group I ribozyme domain: Principles of RNA packing. Science 273(Sept. 20):1678.

Ekland, E.H., and D.P. Bartel. 1996. RNA world begins to add up. Science News 150(Aug. 10):93.

Pennisi, E. 1993. High-tech gene therapy to target HIV. Science News 144(Sept. 18):182.

Thirumalai, D. 1998. Native secondary structure formation in RNA may be a slave to tertiary folding. Proceedings of the National Academy of Sciences 95(Sept. 29):11506.

Travis, J. 1998. Inner strength. Science News 153(March 14):174.

______. 1996. RNA challenges cancer. Science News 149(June 15):381.

______. 1996. Gene therapy strategy repairs RNA, not DNA. Science News 149(June 8):357.

______. 1995. Artificial RNA enzymes: Big and fast. Science News 148(July 22):53.

 

Sources:

Scott K. Silverman
University of Colorado, Boulder
Department of Chemistry and Biochemistry
Campus Box 215
Boulder, CO 80309

Ignacio Tinoco, Jr.
University of California, Berkeley
Chemistry Department
Berkeley, CA 94720-1460

From Science News, Vol. 154, No. 15, October 10, 1998, p. 228.
Copyright Ó 1998 by Science Service.

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