Stopgap measure could limit stroke damage
The puzzling brain damage that continues for days after a stroke may depend on conduits between brain cells called gap junctions.
References:
Budd, S.L., and S.A. Lipton. 1998. Calcium tsunamis: Do astrocytes transmit cell death messages via gap junctions during ischemia? Nature Neuroscience 1(October):431.
Lin, J.H.-C. . . . S. Goldman, and M. Nedergaard. 1998. Gap-junction-mediated propagation and amplification of cell injury. Nature Neuroscience 1(October):494.
Further Readings:
1994. Glia: The brains other cells. Science 266(Nov. 11):970.
Sources:
Steven Goldman
Cornell University Medical Center
Department of Neurology and Neuroscience
New York, NY 10021Jane H.-C. Lin
New York Medical College
Department of Pathology
Valhalla, NY 10595Stuart A. Lipton
Brigham and Womens Hospital
CNS Research Institute
221 Longwood Avenue
LMRC First Floor
Boston, MA 02115Maiken Nedergaard
New York Medical College
Department of Cell Biology and Anatomy
Department of Neurosurgery
Valhalla, NY 10595
From Science News, Vol. 154, No. 15, October 10, 1998,
p. 230.
Copyright Ó 1998 by Science Service.
10/10/98
copyright 1998 ScienceService