Race to find human stem cells ends in tie
Two research teams have isolated seemingly immortal human cells that can give rise to any cell type in the body.
References:
Brüstle, O. . . . R.D.G. McKay. 1998. Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats. Nature Biotechnology 16(November):1040.
Flax, J.D. . . . E.Y. Snyder. 1998. Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes. Nature Biotechnology 16(November):1033.
Gearhart, J. 1998. New potential for human embryonic stem cells. Science 282(Nov. 6):1061.
Shamblott, M.J. . . . J.D. Gearhart. 1998. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proceedings of the National Academy of Sciences 95(Nov. 10):13726.
Thompson, J.A., et al. 1998. Embryonic stem cell lines derived from human blastocysts. Science 282(Nov. 6):1145.
Further Readings:
1995. Monkeying around with stem cells. Science News 148(Aug. 26):139.
Travis, J. 1997. Human embryonic stem cells found? Science News 152(July 19):36.
Zigova, T., and P.R. Sanberg. 1998. The rising star of neural stem cell research. Nature Biotechnology 16(November):1007.
Sources:
John D. Gearhart
Johns Hopkins University
School of Medicine
Department of Gynecology and Obstetrics
600 North Wolfe Street
Park Building B2-210
Baltimore, MD 21287Ronald D.G. McKay
National Institutes of Health
National Institute of Neurological Disorders and Stroke
Laboratory of Molecular Biology
Bethesda, MD 20892-4092Evan Y. Snyder
Children's Hospital
Harvard Medical School
Departments of Neurology, Pediatrics, and Neurosurgery
Boston, MA 02115James A. Thompson
University of Wisconsin, Madison
Wisconsin Regional Primate Research Center
Madison, WI 53715
From Science News, Vol. 154, No. 19, November 7,
1998, p. 293.
Copyright Ó 1998 by Science Service.
copyright 1998 ScienceService