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  Muscle cells in damaged hearts may divide

A finding that human heart muscle cells can divide may help researchers discover how to regenerate tissue damaged by heart attacks.

 

References:

Kajstura, J.A., P. Anversa, et al. 1998. Myocyte proliferation in end-stage cardiac failure in humans. Proceedings of the National Academy of Science 95(July 21):8801.

 

Further Readings:

Anversa, P., and J. Kajstura. 1998. Ventricular myocytes are not terminally differentiated in the adult mammalian heart. Circulation Research 83(July 13):1.

Claycomb, W.C., et al. 1998. HL-1 cells: A cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proceedings of the National Academy of Sciences 95(March 17):2979.

Soonpaa, M.H., and L.J. Field. 1998. Survey of studies examining mammalian cardiomyocyte DNA synthesis. Circulation Research 83(July 13):15.

 

Sources:

Piero Anversa
New York Medical College
Department of Medicine
Vosburgh Pavilion, Room 302A
Valhalla, NY 10595

Kenneth R. Chien
University of California
San Diego Department of Medicine
0613-C 200 West Arbor Drive
San Diego, CA 92103

 

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