The
Incredible Shrinking Laboratory
Microchips may revolutionize chemistry as they did computers
Chemistry labs etched on silicon, glass, and plastic surfaces promise to speed chemical synthesis, diagnostic tests, and gene sequencing.
References:
Cheng, J., et al. 1998. Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricated bioelectronic chips. Nature Biotechnology 16(June):541.
______. 1998. Isolation of cultured cervical carcinoma cells mixed with peripheral blood cells on a bioelectronic chip. Analytical Chemistry 70(June 1):2321.
Further Readings:
Kricka, L.J. 1998. Revolution on a square centimeter. Nature Biotechnology 16(June):513.
Pfost, D.R. 1998. The engineering of drug discovery. Nature Biotechnology 16(April):313.
Travis, J. 1997. Chips ahoy. Science News 151(March 8):144.
Sources:
Jing Cheng
Nanogen, Inc.
10398 Pacific Center Court
San Diego, CA 92121
Web site: http://www.nanogen.comPaul Heaney
Orchid Biocomputer, Inc.
201 Washington Road
Princeton, NJ 08543-2197Michael R. Knapp
Caliper Technologies Corp.
1275 California Avenue
Palo Alto, CA 94304
Web site: http://www.calipertech.comPeter Wilding
University of Pennsylvania
School of Medicine
Department of Pathology and Laboratory Medicine
3400 spruce Street
Philadelphia, PA 19104
copyright 1998 ScienceService