Dialing up an Embryo
Are olfactory receptors digits in a developmental code?
The molecules that detect odors may also guide embryonic development.
References:
Dreyer, W.J. 1998. The area code hypothesis revisited: Olfactory receptors and other related transmembrane receptors may function as the last digits in a cell surface code for assembling embryos. Proceedings of the National Academy of Sciences 95(Aug. 4):9072.
Further Readings:
Dynes, J.L., and J. Ngai. 1998. Pathfinding of olfactory neuron axons to stereotyped glomerular targets revealed by dynamic imaging in living zebrafish embryos. Neuron 20(June):1081.
Mombaerts, P., et al. 1996. Visualizing an olfactory sensory map. Cell 87(Nov. 15):675.
Sources:
William J. Dreyer
California Institute of Technology
Division of Biology
Pasadena, CA 91125Peter Mombaerts
The Rockefeller University
1230 York Avenue, Box 242
New York, NY 10021John Ngai
University of California, Berkeley
Department of Molecular & Cell Biology
142 Life Sciences Addition #3200
Berkeley, CA 94720-3200
copyright 1998 ScienceService