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Grafted muscle cells aid damaged hearts

Researchers boosted pumping efficiency in damaged rabbit hearts by introducing leg muscle cells.

 

References:

Kajstura, J. . . . P. Anversa, et al. 1998. Myocyte proliferation in end-stage cardiac failure in humans. Proceedings of the National Academy of Sciences 95(July 21):8801.

Taylor, D., et al. 1998. Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation. Nature Medicine 4(August):929.

 

Further Readings:

Brainard, J. 1998. Muscle cells in damaged hearts may divide. Science News 154(July 25):54.

Soonpaa, M.H., et al. 1994. Formation of nascent intercalated disks between grafted fetal cardiomyocytes and host myocardium. Science 264(April 1):98.

Watt, D.J., et al. 1994. Migration of muscle cells. Nature 368(March 31):406.

Sources:

Ray C.J. Chiu
McGill University
Montreal General Hospital
University Surgery Clinic
1650 Cedar Avenue
Montreal, Quebec H3G 1A4
Canada

Doris A. Taylor
Duke University Medical Center
Department of Medicine
Division of Cardiology
P.O. Box 3327
Durham, NC 27710

 

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