References & Sources  -  August 1, 1998

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Ring around the virus: RNA packs in the DNA

A circle of RNA helps viruses stuff DNA into their empty shells.

 

References:

Guo, P., et al. 1998. Inter-RNA interaction of phage f 29 pRNA to form a hexameric complex for viral DNA transportation. Molecular Cell (July):149.

Hendrix, R.W. 1998. Bacteriophage DNA packaging: RNA gears in a DNA transport machine. Cell 94(July 24):147.

Zhang, F. . . . D. Anderson. 1998. Function of hexameric RNA in packaging of bacteriophage f 29 DNA in vitro. Molecular Cell 2(July):141.

Further Readings:

Chen, C., and P. Guo. 1997. Sequential action of six virus-encoded DNA-packaging RNAs during phage phi29 genomic DNA translocation. Journal of Virology 71:3864.

Sources:

Dwight Anderson
University of Minnesota
Departments of Microbiology and Oral Science
Minneapolis, MN 55455

Peixuan Guo
Purdue University
Purdue Biochemistry and Molecular Biology Program
Department of Pathobiology
West Lafayette, IN 47907

Roger W. Hendrix
University of Pittsburgh
Pittsburgh Bacteriophage Institute
Department of Biological Sciences
Pittsburgh, PA 15260

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