References & Sources

Collagen transplant replaces rabbit artery

Using collagen from pig intestines and cow tendons, researchers have made blood vessels that work in rabbits without clogging or inducing immune rejection.

References:

Huynh, T. . . . and S. Sullivan. 1999. Remodeling of an acellular collagen graft into a physiologically responsive neovessel. Nature Biotechnology 17(November):1083.

Further Readings:

Williams, S.K., B.E. Jarrell, and L.B. Kleinert. 1994. Endothelial cell transplantation onto porcine arteriovenous grafts evaluated using a canine model. Journal of Investigative Surgery 7:503.

Heart and Stroke Facts: Statistical Supplement, American Heart Association. Available at http://www.americanheart.org/statistics.

Additional information can be found at the American Heart Association at http://www.americanheart.org.

Sources:

Timothy Scott-Burden
Texas Heart Institute
Texas Medical Center
Mailstop Code 2-255
P.O. Box 20345
Houston, TX 77225

Susan J. Sullivan
Organogenesis, Inc.
150 Dan Road
Canton, MA 02021

John T. Watson
National Institutes of Health
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Room 9178
Bethesda, MD 20892

From Science News, Vol. 156, No. 18, October 30, 1999, p. 279. Copyright © 1999, Science Service.