Medicinal EMFs

Properly applied, electric and magnetic fields appear to help people at risk for osteoporosis or related bone ailments.

Aaron, R.K., D.M. Ciombor, et al. 1999. Power frequency fields promote cell differentiation coincident with an increase in transforming growth factor-b ₁ expression. Bioelectromagnetics 20(August):453.

Huang, R.P., C.T. Rubin, and K.J. McLeod. 1999. Changes in postural muscle dynamics as a function of age. Journal of Gerontology: Biological Sciences SUA 8(August).

Longo, F.M. . . . and B.F. Sisken. 1999. Electromagnetic fields influence NGF activity and levels following sciatic nerve transection. Journal of Neuroscience Research 55:230.

Markov, M.S., and A.A. Pilla. 1999. Static m T-level magnetic fields modulate myosin phosphorylation via kinetic effects on calcium binding to calmodulin. In Proceedings, 2nd World Congress on Electricity and Magnetism in Biology and Medicine. Plenum Press, New York.

McLeod, K.J. . . . and C.T. Rubin. 1999. Frequency and duration optimization of dynamic loading protocols for the reversal of osteopenia. Meeting of the Orthopaedic Research Society. February. Anaheim, Calif.

McLeod, K.J., C.T. Rubin, et al. 1998. Skeletal cell stresses and bone adaptation. American Journal of the Medical Sciences 316(September):176.

Midkiff, P., and B.F. Sisken. 1999. Nerve regeneration in vitro: Mechanism of stimulation with pulsed radiofrequency fields. Meeting of the Bioelectromagnetic Society. June. Long Beach.

Muehsam, D.J., and A.A. Pilla. 1999. The sensitivity of cells and tissues to exogenous fields: Effects of target system initial state. Bioelectrochemistry and Bioenergetics 48(February):35.

Pilla, A.A. 1999. State of the art in electromagnetic therapeutics: Soft tissue applications. In Proceedings, 2nd World Congress on Electricity and Magnetism in Biology and Medicine. Plenum Press. New York.

Pilla, A.A. . . . and B.F. Sisken. 1999. EMF signals and ion/ligand binding kinetics: Prediction of bioeffective waveform parameters. Bioelectrochemistry and Bioenergetics 48(February):27.

Ryaby, J.T. 1998. Clinical effects of electromagnetic and electric fields on fracture healing. Clinical Orthopaedics 355(October):S205.

Fitzsimmons, R.J., J.T. Ryaby, et al. 1995. Combined magnetic fields increase insulin-like growth factor-II in TE-85 human osteosarcoma bone cell cultures. Endocrinology 136:3100.

Koth, L.C. . . . A.A. Pilla, et al. 1999. Effect of pulsed radio frequency stimulation on wound healing: A double-blind pilot clinical study. In Proceedings, 2nd World Congress on Electricity and Magnetism in Biology and Medicine. Plenum Press. New York.

Markov, M.S., and A.A. Pilla. 1997. Weak static magnetic field modulation of myosin phosphorylation in a cell-free preparation: Calcium dependence. Bioelectrochemistry and Bioenergetics 43:233.

McLeod, K.J., and C.T. Rubin. 1992. The effect of low-frequency electrical fields on osteogenesis. Journal of Bone and Joint Surgery.

______. 1990. Frequency specific modulation of bone adaptation by induced electric fields. Journal of Theoretical Biology 145:385.

Pilla, A.A. 1993. State of the art in electromagnetic therapeutics. In Electricity and Magnetism in Biology and Medicine. Blank, M., ed. San Francisco Press.

Pilla, A,A., D.J. Muehsam, and M.S. Markov. A dynamical systems/Larmor precession model for weak magnetic field bioeffects: Ion binding and orientation of bound water molecules. Bioelectrochemistry and Bioenergetics 43:239.

Raloff, J. 1999. EMFs—doubts linger over possible risks. Science News 156(July 3):12.

______. 1999. Electromagnetic fields may damage hearts. Science News 155(Jan. 30):70.

______. 1998. Electromagnetic fields may trigger enzymes. Science News 153(Feb. 21):119.

______. 1998. EMFs’ biological influences. Science News 153(Jan. 10):29.

Rubin, C.T. . . . and K.J. McLeod. 1993. Optimization of electric field parameters for the control of bone remodeling: Exploitation of an indigenous mechanism for the prevention of osteopenia. Journal of Bone and Mineral Research 8:S573.

Sisken, B.F., and J. Walker. 1995. Therapeutic aspects of electromagnetic fields for soft-tissue healing. In Electromagnetic Fields: Biological Interactions and Mechanisms. American Chemical Society, Washington, D.C.

Sisken, B.F., J.M. Jacob, and J.L. Walker. 1995. Acute treatment with pulsed electromagnetic fields and its effect on fast axonal transport in normal and regenerating nerve. Journal of Neuroscience Research 42:692.

Sisken, B.F., et al. 1989. Stimulation of rat sciatic nerve regeneration with pulsed electromagnetic fields. Brain Research 485:309.

Walker, J.L. . . . and B.F. Sisken. 1994. enhancement of functional recovery following a crush lesion to the rat sciatic nerve by exposure to pulsed electromagnetic fields. Experimental Neurology 125:302.

Roy K. Aaron
Brown University School of Medicine
Department of Orthopaedics
Providence, RI 02906

Carl T. Brighton
University of Pennsylvania
School of Medicine
Department of Orthopaedic Surgery
425 Stemmler/6081
Philadelphia, PA 19104

Deborah M. Ciombor
Brown University School of Medicine
Department of Orthopaedics
Providence, RI 02906

Diane Cullen
Creighton University
Department of Medicine-Osteoporosis
SJH Room 4820
Omaha, NE 68178

Deborah M. Ciomber
Brown University
Department of Bio. Med. Orthopaedics
Box G-RI
Providence, RI 02912

Kenneth J. McLeod
State University of New York, Stony Brook
Program in Bioengineering
Health Science Center
T18-030
Stony Brook, NY 11794-8181

Arthur A. Pilla
Mount Sinai School of Medicine
Department of Orthopaedics
Bioelectrochemistry Laboratory
New York, NY 10029

Jack Ryaby
Exogen, Inc.
10 Constitution Avenue
P.O. Box 6860
Piscataway, NJ 08855

Betty F. Sisken
University of Kentucky
Department of Anatomy and Neurobiology
Center for Biomedical Engineering
Lexington, KY 40506

From Science News, Vol. 156, No. 20, November 13, 1999, p. 316. Copyright © 1999, Science Service.