References & Sources

HIV-like gene lies buried in human DNA

Viral DNA long buried in the human genome contains a gene for a protein also used by the AIDS virus.

References:

Yang, J. . . . and B.R. Cullen. 1999. An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein. Proceedings of the National Academy of Sciences 96(Nov. 9):13404.

Further Readings:

Löwer, R., J. Löwer, and R. Kurth. 1996. The viruses in all of us: Characteristics and biological significance of human endogenous retrovirus sequences. Proceedings of the National Academy of Sciences 93(May):5177.

Towler, E.M., et al. 1998. Functional characterization of the protease of human endogenous retrovirus, K10: Can it complement HIV-1 protease? Biochemistry (November). (See http://pubs.acs.org/hotartcl/bio/bi9818927_rev.html.)

Sources:

Bryan R. Cullen
Duke University Medical Center
Department of Genetics
Box 3025
Durham, NC 27710

From Science News, Vol. 156, No. 20, November 13, 1999, p. 311. Copyright © 1999, Science Service.