References & Sources

Clogged arteries block hormone effects

Atherosclerosis might block genes for estrogen receptors, perhaps explaining why a large study of hormone-replacement therapy didn’t show the expected benefit of estrogen against heart disease.

References:

Post, W.S., P.J. Goldschmidt, et al. 1999. Methylation of the estrogen receptor gene is associated with aging and atherosclerosis in the cardiovascular system. Cardiovascular Research 43(Sept. 1):985.

Further Readings:

Christensen, D. 1999. Designer estrogens. Science News 156(Oct. 16):252.

Sources:

Pascal J. Goldschmidt
Ohio State University
Heart and Lung Institute
Columbus, OH 43210

From Science News, Vol. 156, No. 19, November 6, 1999, p. 303. Copyright © 1999, Science Service.