| Bacteria offer
lessons to drug makers
Newly unveiled
tactics used by bacteria in smiting other microbes suggest approaches
for making new and better antibiotics.
References:
Breukink, E., et
al. 1999. Use of the cell wall precursor Lipid II by a
pore-forming peptide antibiotic. Science 286(Dec. 17):2361.
Further Readings:
Crandall, A.D.,
and T.J. Montville. 1998. Nisin resistance in Listeria
monocytogenes ATCC 700302 is a complex phenotype. Applied
Environmental Microbiology 64:231.
Mazzotta, A.S.,
A.D. Crandall, and T.J. Montville. 1997. Nisin resistance in Clostridium
botulinum spores and vegetative cells. Applied Environmental
Microbiology 63:2654.
Raloff, J. 1999. Waterways carry antibiotic resistance. Science
News 155(June 5):356.
______. 1998. Livestock’s role in antibiotic
resistance. Science News 154(July 18):39.
______. 1998. Staging germ warfare in foods.
Science News 153(Feb. 7):89.
______. 1995.
Defending us from our dirty mouths. Science News 147(March
18):166.
Seppa, N. 1997. A new gap in the antibiotic
arsenal. Science News 151(June 7):348.
Smaglik, P. 1997.
Proliferation of pills. Science News 151(May 17):310.
Wu, C. 1999.
Beyond vancomycin. Science News 155(April 24):268.
Sources:
Eefjan Breukink
Utrecht University
Department of Biochemistry of Membranes
Center of Biomembranes and Lipid Enzymology
Institute for Biomembranes
Padualaan 8
3584 CH Utrecht
Netherlands
Todd R.
Klaehammer
North Carolina State University
Department of Food Science - Box 7624
Southeast Dairy Foods Research Center
Raleigh, NC 27695-7624
Thomas J.
Montville
Rutgers University
Department of Food Science
65 Dudley Road
New Brunswick, NJ 08901-8520
From Science
News, Vol. 156, No. 25 & 26, December 18 & 25, 1999, p. 390.
Copyright © 1999, Science Service. |