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More Than the Brain's Drain
Does cerebrospinal fluid help the brain convey messages?
The fluid that bathes the brain and spinal cord may be used by those organs to send signals for sleep, appetite, and sex.
References:
Rubenstein, E. 1998. Lancet 351(Jan. 24):283.
Silver, R., and M.N. Lehman 1998. Workshop on the CSF as a communication pathway of the brain. Meeting of the Society for Neuroscience. November. Los Angeles.
Further Readings:
1996. Feasting on neuropeptide Y research. Science News 150(July 27):63.
Quan, N. . . . M. Herkenham. 1997. Induction of inhibitory factor kBa mRNA in the central nervous system after peripheral lipopolysaccharide administration: An in situ hybridization histochemistry study in the rat. Proceedings of the National Academy of Sciences 94(September):10985.
Seachrist, L. 1995. Tired cats make lipid sleep hormone. Science News 147(June 10:)356.
Silver, R. . . . M.N. Lehman. 1996. A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 382(Aug. 29):810.
Skinner, D.C., et al. 1997. Simultaneous measurement of gonadotropin-releasing hormone in the third ventricular cerebrospinal fluid and hypophyseal portal blood of the ewe. Endocrinology 138:4699.
Sources:
Miles Herkenham
National Institute of Mental Health
Section on Functional Neuroanatomy
Building 36, Room 2D15
Bethesda, MD 20892-4070
James M. Krueger
Washington State University
Wagner Hall, Room 205
Pullman, WA 99164-6520
Michael N. Lehman
University of Cincinnati
College of Medicine
Department of Cell Biology, Neurobiology, and Anatomy
Cincinnati, OH 45267
Charles Nicholson
New York University Medical Center
Department of Physiology and Biophysics
550 First Avenue
New York, NY 10016
Edward Rubenstein
Stanford University School of Medicine
3000 Pasteur Drive
Stanford, CA 94305
Rae Silver
Columbia University
Barnard College
Department of Psychology
3009 Broadway
New York, NY 10027
Donal C. Skinner
Institut National de la Recherche Agronomique
Station de Physiologie de la Reproduction
Nouzilly 37380
France
From Science News, Vol. 155, No. 4, January 23, 1999, p. 58. Copyright © 1999, Science Service.