< Back to Contents
Multiplied immune cells combat HIV
Immune cells called cytoxic T lymphocytes can be taken from a HIV-positive patient, massively replicated, and reinjected into the individual to temporarily fight the AIDS virus.
References:
Brodie, S.J. . . . and S.R. Riddell. 1999. In vivo migration and function of transferred HIV-1-specific cytotoxic T cells. Nature Medicine 5(January):34.
Further Readings:
Fleury, S., et al. 1998. Limited CD4 T-cell renewal in early HIV-1 infection: Effect of highly active antiviral therapy. Nature Medicine 4:794.
Koenig, S., et al. 1995. Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression. Nature Medicine 1(April):330.
Pantaleo, G. 1999. Unraveling the strands of HIV's web. Nature Medicine 5(January):27.
______. 1997. How immune-based interventions can change HIV therapy. Nature Medicine 3:483.
Zhang, Z-Q., et al. 1998. Kinetics of DC4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. Proceedings of the National Academy of Sciences 95(February):1154.
Sources:
Xia Jin
Aaron Diamond AIDS Research Institute
455 First Avenue, 7th Floor
New York, NY 10016
Stanley R. Riddell
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North
D3-100
Seattle, WA 98109
From Science News, Vol. 155, No. 4, January 23, 1999, p. 52. Copyright © 1999, Science Service.
