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New combination vaccine may fight malaria
A gene synthesized from a malaria parasite's DNA produces a protein that stimulates an immune response against the parasite in all its life stages.
References:
Shi, Y.P. . . . and A.A. Lal. 1999. Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine. Proceedings of the National Academy of Sciences 96(Feb. 16):1615.
Further Readings:
Shell, E.R. 1997. Resurgence of a deadly disease. Atlantic Monthly. 280(August):45.
Travis, J. 1997. Gene creates malaria drug resistance. Science News 152(Nov. 29):340.
______. 1997. Hitting malaria parasites early and hard. Science News 151(Jan. 11):23.
Sources:
Stephen L. Hoffman
Naval Medical Research Institute
12300 Washington Avenue
Rockville, MD 20852
Altaf A. Lal
Centers for Disease Control and Prevention
Division of Parasitic Diseases
Molecular Vaccine Section
Mailstop Code F-12
4770 Buford Highway
Chamblee, GA 30341-3717
Louis H. Miller
National Institutes of Health
Building 4, Room 126
Bethesda, MD 20892
From Science News, Vol. 155, No. 8, February 20, 1999, p. 117. Copyright © 1999, Science Service.
