Why cutting fats may harm the heart
For many people, low-fat diets may increase heart-disease risks by triggering adverse changes among carrier molecules that shuttle fatty substances through the blood.
References:
Dreon, D.M. . . . and R.M. Krauss. 1999. A very low-fat diet is not associated with improved lipoprotein profiles in men with a predominance of large, low-density lipoproteins. American Journal of Clinical Nutrition 69(March):411.
Dreon, D.M. . . . and R.M. Krauss. 1994. Low-density lipoprotein subclass patterns and lipoprotein response to a reduced fat diet in men. FASEB Journal 8(January):122.
Williams, P.T., D.M. Dreon, and R.M. Krauss. 1995. Effects of dietary fat on high-density-lipoprotein subclasses are influenced by both apolipoprotein E isoforms and low-density-lipoprotein subclass patterns. American Journal of Clinical Nutrition 61:1234.
Further Readings:
Dreon, D.M. . . . R.M. Krauss. 1998. Change in dietary saturated fat intake is correlated with change in mass of large low-density-lipoprotein particles in men. American Journal of Clinical Nutrition 67(May):828.
Dreon, D.M. . . . R.M. Krauss. 1997. LDL subclass patterns and lipoprotein response to a low-fat, high-carbohydrate diet in women. Arteriosclerosis, Thrombosis, and Vascular Biology 17(April):707.
Krauss, R.M., and D.M Dreon. 1995. Low-density-lipoprotein subclasses and response to a low-fat diet in healthy men. American Journal of Clinical Nutrition 62:478S.
Raloff, J. 1998. High-fat and healthful. Science News 154(Nov. 21):328.
______. 1996. The baddest of the bad cholesterols? Science News 150(Sept. 21):182.
______. 1996. More on those "really bad" LDLs . . . Science News Online (Sept. 21).
______. 1994. Margarine is anything but a marginal fat. Science News 145(May 21):325.
Sources:
Ronald M. Krauss
University of California, Berkeley
Department of Molecular and Nuclear Medicine
Life Sciences Division
Lawrence Berkeley National Laboratory
Donner Laboratory, Room 465
One Cyclotron Road
Berkeley, CA 94720
E-mail: rmkrauss@lbl.gov
Meir J. Stampfer
Harvard School of Public Health
Department of Epidemiology and Nutrition
181 Longwood Avenue
Boston, MA 02115
From Science News, Vol. 155, No. 12, March 20, 1999, p. 180. Copyright © 1999, Science Service.