Study links acid reflux, esophageal cancer
Swedish researchers have discovered a correlation between heartburn and an esophageal cancer called adenocarcinoma.
Lagergren, J., et al. 1999. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. New England Journal of Medicine 340(March 18):825.
Chow, W.H., et al. 1995. The relation of gastroesophageal reflux disease and its treatment to adenocarcinomas of the esophagus and gastric cardia. Journal of the American Medical Association 274:474.
Cohen, S., and H.P. Parkman. 1999. Heartburna serious symptom. New England Journal of Medicine 340(March 18):878.
Drewitz, D.J., R.E. Sampliner, and H.S. Garewal. 1997. The incidence of adenocarcinoma in Barrett's esophagus: A prospective study of 170 patients followed 4.8 years. American Journal of Gastroenterology 92:212.
Pera, M., et al. 1993. Increasing incidence of adenocarcinoma of the esophagus and esophagogastric junction. Gastroenterology 104:510.
Scott, M., and A.R. Gelhot. 1999. Gastroesophageal reflux disease: Diagnosis and management. American Family Physician 59(March 1):1161.
David Y. Graham
Veterans Affairs Medical Center
Mailstop Code 111D
2002 Holcombe Boulevard
Houston, TX 77030
Karolinska Institutet Danderyd Hospital
Division of Surgery
182 88 Danderyd
S-171 77 Stockholm
Henry P. Parkman
School of Medicine
3401 North Broad Street
Philadelphia, PA 19140
From Science News, Vol. 155, No. 12, March 20, 1999, p. 182. Copyright © 1999, Science Service.