Study links acid reflux, esophageal cancer
Swedish researchers have discovered a correlation between heartburn and an esophageal cancer called adenocarcinoma.
References:
Lagergren, J., et al. 1999. Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. New England Journal of Medicine 340(March 18):825.
Further Readings:
Chow, W.H., et al. 1995. The relation of gastroesophageal reflux disease and its treatment to adenocarcinomas of the esophagus and gastric cardia. Journal of the American Medical Association 274:474.
Cohen, S., and H.P. Parkman. 1999. Heartburn—a serious symptom. New England Journal of Medicine 340(March 18):878.
Drewitz, D.J., R.E. Sampliner, and H.S. Garewal. 1997. The incidence of adenocarcinoma in Barrett's esophagus: A prospective study of 170 patients followed 4.8 years. American Journal of Gastroenterology 92:212.
Pera, M., et al. 1993. Increasing incidence of adenocarcinoma of the esophagus and esophagogastric junction. Gastroenterology 104:510.
Scott, M., and A.R. Gelhot. 1999. Gastroesophageal reflux disease: Diagnosis and management. American Family Physician 59(March 1):1161.
Sources:
David Y. Graham
Veterans Affairs Medical Center
Mailstop Code 111D
2002 Holcombe Boulevard
Houston, TX 77030
Jesper Lagergren
Karolinska Institutet Danderyd Hospital
Division of Surgery
182 88 Danderyd
S-171 77 Stockholm
Sweden
Henry P. Parkman
Temple University
School of Medicine
G.I. Section
3401 North Broad Street
Philadelphia, PA 19140
From Science News, Vol. 155, No. 12, March 20, 1999, p. 182. Copyright © 1999, Science Service.
