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Volume 155, Number 18 (May 1, 1999)

References & Sources
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Does obesity trigger chronic inflammation?

Overweight people show symptoms of chronic, low-grade inflammation, perhaps indicating early atherosclerosis.

References:

Visser, M., et al. 1999. Elevated inflammation status in obesity: NHANES III (Abstract 685.3). FASEB Journal 13(March 15):A925.

Further Readings:

Fried, S.K., D.A. Bunkin, and A.S. Greenberg. 1998. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid. Journal of Clinical Endocrinology and Metabolism 83(March):847.

Fackelmann, K.A. 1997. Harbinger of a heart attack. Science News 151(June 14):374.

Mohamed-Ali, V. . . . S. Klein, et al. 1997. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-a, in vivo. Journal of Clinical Endocrinology and Metabolism 82(December):4196.

Pasceri, V., et al. 1998. Association of virulent Helicobacter pylori strains with ischemic heart disease. Circulation 97(May 5):1675.

Ridker, P.M., et al. 1998. Inflammation, pravastatin, and the risk of coronary events after myocardial infarction in patients with average cholesterol levels. Circulation 98(Sept. 1):839.

______. 1998. C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. Circulation 97(May 26):2007.

______. 1998. Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation 97(Feb. 10):425.

Ridker, P.M. 1998. Inflammation, infection, and cardiovascular risk: How good is the clinical evidence? Circulation 97(May 5):1671.

Tracy, R.P. 1998. Inflammation in cardiovascular disease: Cart, horse, or both? Circulation 97(May 26):2000.

Sources:

Paul M. Ridker
Brigham and Women's Hospital
Cardiology Department
75 Francis Street
Boston, MA 02115

Marjolein Visser
Vrije University
Van der Boechorststraat 7
1081 BT Amsterdam
Netherlands

From Science News, Vol. 155, No. 18, May 1, 1999, p. 278. Copyright © 1999, Science Service.


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