| An Electrifying
DNA Debate
New evidence
explains how DNA conducts charge
DNA’s ability to
conduct electrons might play a role in radiation damage and mutation
repair.
References:
Harriman, A.
1999. Electron Tunneling in DNA. Angewandte Chemie International
Edition 38:945.
Henderson, P.T.
. . . and G.B. Schuster. 1999. Long-distance charge transport in
duplex DNA: The phonon-assisted polaron-like hopping mechanism. Proceedings
of the National Academy of Sciences 96(July 20):8353.
Rajski, S.R. . .
. and J.K. Barton. 1999. Protein-modulated DNA electron
transfer. Journal of the American Chemical Society 121(June
16):5615.
Wan, C. . . .
J.K. Barton, and A.H. Zewail. 1999. Femtosecond dynamics of
DNA-mediated electron transfer. Proceedings of the National Academy
of Sciences 96(May 25):6014.
Further Readings:
1997. Double helix
does chemistry at a distance—but how? Science 275(March
7):1420.
Castleman Jr., A.W.,
Q. Zhong, and S.M. Hurley. 1999. Femtochemistry uncovers the nature of
electron transfer reactions. Proceedings of the National Academy of
Sciences 96(April 13):4219.
Kelley, S.O., and
J.K. Barton. 1999. Electron transfer between bases in double helical
DNA. Science 283(Jan. 15):375.
Lewis, F.D., et
al. 1997. Distance-dependent electron transfer in DNA hairpins. Science
277(Aug. 1):673.
Murphy, C.J. . . .
J.K. Barton. 1993. Long-range photoinduced electron transfer through a
DNA helix. Science 262(Nov. 12):1025.
Núñez, M.E., D.B.
Hall, and J.K. Barton. 1999. Long-range oxidative damage to DNA: Effects
of distance and sequence. Chemistry & Biology 6(February):85.
Wilson, E.K. 1998.
DNA’s conductance still confounds. Chemical & Engineering News
(July 27):51.
Sources:
Jacqueline K.
Barton
California Institute of Technology
Department of Chemistry, M/C 127-72
Pasadena, CA 91125
Web site: http://www.cco.caltech.edu/~jkbgrp/
David Beratan
Chevron Science Center
Department of Chemistry
219 Parkman Avenue
Pittsburgh, PA 15260
Web site: http://www.chem.pitt.edu/faculty/beratan.html
Anthony Harriman
Université Louis Pasteur
Ecole Européenne de Chimie,
Polymeres, et Matériaux
25 rue Becquerel
F-67087 Strasbourg Cedex
France
Frederick D.
Lewis
Northwestern University
Department of Chemistry
2145 Sheridan Road
Evanston, IL 60208-3113
Web site: http://www.chem.nwu.edu/brochure/lewis.html
Gary B. Schuster
Georgia Institute of Technology
School of Chemistry and Biochemistry
Atlanta, GA 30332-0400
Web site: http://www.chemistry.gatech.edu/faculty/schuster/schuster.html
Nicholas J.
Turro
Columbia University
Department of Chemistry
3000 Broadway
Mailstop Code 3119
New York, NY 10027
Web sites: http://www.columbia.edu/cu/chemistry/faculty/njt.html
http://turmac13.chem.columbia.edu/default.html
From Science
News, Vol. 156, No. 7, August 14, 1999, p. 104. Copyright © 1999,
Science Service. |