References & Sources

An Electrifying DNA Debate

New evidence explains how DNA conducts charge

DNA’s ability to conduct electrons might play a role in radiation damage and mutation repair.

References:

Harriman, A. 1999. Electron Tunneling in DNA. Angewandte Chemie International Edition 38:945.

Henderson, P.T. . . . and G.B. Schuster. 1999. Long-distance charge transport in duplex DNA: The phonon-assisted polaron-like hopping mechanism. Proceedings of the National Academy of Sciences 96(July 20):8353.

Rajski, S.R. . . . and J.K. Barton. 1999. Protein-modulated DNA electron transfer. Journal of the American Chemical Society 121(June 16):5615.

Wan, C. . . . J.K. Barton, and A.H. Zewail. 1999. Femtosecond dynamics of DNA-mediated electron transfer. Proceedings of the National Academy of Sciences 96(May 25):6014.

Further Readings:

1997. Double helix does chemistry at a distance—but how? Science 275(March 7):1420.

Castleman Jr., A.W., Q. Zhong, and S.M. Hurley. 1999. Femtochemistry uncovers the nature of electron transfer reactions. Proceedings of the National Academy of Sciences 96(April 13):4219.

Kelley, S.O., and J.K. Barton. 1999. Electron transfer between bases in double helical DNA. Science 283(Jan. 15):375.

Lewis, F.D., et al. 1997. Distance-dependent electron transfer in DNA hairpins. Science 277(Aug. 1):673.

Murphy, C.J. . . . J.K. Barton. 1993. Long-range photoinduced electron transfer through a DNA helix. Science 262(Nov. 12):1025.

Núñez, M.E., D.B. Hall, and J.K. Barton. 1999. Long-range oxidative damage to DNA: Effects of distance and sequence. Chemistry & Biology 6(February):85.

Wilson, E.K. 1998. DNA’s conductance still confounds. Chemical & Engineering News (July 27):51.

Sources:

Jacqueline K. Barton
California Institute of Technology
Department of Chemistry, M/C 127-72
Pasadena, CA 91125
Web site: http://www.cco.caltech.edu/~jkbgrp/

David Beratan
Chevron Science Center
Department of Chemistry
219 Parkman Avenue
Pittsburgh, PA 15260
Web site: http://www.chem.pitt.edu/faculty/beratan.html

Anthony Harriman
Université Louis Pasteur
Ecole Européenne de Chimie,
Polymeres, et Matériaux
25 rue Becquerel
F-67087 Strasbourg Cedex
France

Frederick D. Lewis
Northwestern University
Department of Chemistry
2145 Sheridan Road
Evanston, IL 60208-3113
Web site: http://www.chem.nwu.edu/brochure/lewis.html

Gary B. Schuster
Georgia Institute of Technology
School of Chemistry and Biochemistry
Atlanta, GA 30332-0400
Web site: http://www.chemistry.gatech.edu/faculty/schuster/schuster.html

Nicholas J. Turro
Columbia University
Department of Chemistry
3000 Broadway
Mailstop Code 3119
New York, NY 10027
Web sites: http://www.columbia.edu/cu/chemistry/faculty/njt.html
http://turmac13.chem.columbia.edu/default.html

From Science News, Vol. 156, No. 7, August 14, 1999, p. 104. Copyright © 1999, Science Service.