References & Sources

Antibodies may treat overdoses, addiction

Antibodies blocked the harmful effects of cocaine and PCP in laboratory rats.

References:

Janda, K.D. 1999. Immunopharmacotherapy for the treatment of cocaine abuse. Meeting of the American Chemical Society. August. New Orleans.

Owens, S.M. 1999. Monoclonal antibodies as short- and long-term antagonists for the treatment of drug abuse. Meeting of the American Chemical Society. August. New Orleans.

Further Readings:

Centofanti, M. 1995. Vaccine triggers cocaine mop-up in rats. Science News 148(Dec. 16):148.

Travis, J. 1998. War on drugs enlists an antibody. Science News 154(Oct. 10):239.

Sources:

Kim D. Janda
Scripps Research Institute
Departments of Chemistry and Molecular Biology
10550 North Torrey Pines Road (BCC582)
La Jolla, CA 92037
Web site: http://www.scripps.edu/chem/janda

S. Michael Owens
University of Arkansas for Medical Sciences
College of Medicine
Departments of Pharmacology and Toxicology
Slot 611, 4301 West Markham Street
Little Rock, AR 72205
Web site: http://www.uams.edu/pharmtox/mowens.htm

Frank Vocci
National Institutes of Health
National Institute on Drug Abuse
Medications Development Division
Bethesda, MD 20892

From Science News, Vol. 156, No. 9, August 28, 1999, p. 134. Copyright © 1999, Science Service.