By a nose, worms reveal new Prozac targets 
Identifying genes
that allow a worm’s nose to respond to Prozac may help explain how the
drug alleviates depression in people.
References:
Choy, R.K.M.,
and J.H. Thomas. 1999. Fluoxetine-resistant mutants in C. elegans
define a novel family of transmembrane proteins. Molecular Cell
4(August):143.
Schafer, W.R.
1999. How do antidepressants work? Prospects for genetic analysis of
drug mechanisms. Cell 98(Sept. 3):551.
Further Readings:
Valenstein, E.S.
1998. Blaming the Brain: The Truth about Drugs and Mental Health.
New York: Free Press. (Available from Science News Books Online
at http://st2.yahoo.com/scibook/blamingbrain.html.)
Sources:
Robert K.M. Choy
University of Washington
Program in Molecular and Cellular Biology
Seattle, WA 98195
William R.
Schafer
University of California, San Diego
Department of Biology
La Jolla, CA 92093-0349
James H. Thomas
University of Washington
Department of Genetics
Program in Molecular and Cellular Biology
Seattle, WA 98195
Elliot S.
Valenstein
University of Michigan, Ann Arbor
Department of Psychology
525 East University
Ann Arbor, MI 48109-1109
From Science
News, Vol. 156, No. 13, September 25, 1999, p. 196. Copyright ©
1999, Science Service. |