Gene tinkering hikes fear and anxiety in mice 
Mice missing a
gene that helps with transmission of GABA, a neurotransmitter, may
represent a model for anxiety-predisposed people.
References:
Anagnostaras,
S.G., M.G. Craske, and M.S. Fanselow. 1999. Anxiety: At the
intersection of genes and experience. Nature Neuroscience
2(September):780.
Crestani, F. . .
. and H. Mohler. 1999. Decreased GABAA-receptor clustering
results in enhanced anxiety and a bias for threat cues. Nature
Neuroscience 2(September):833.
Sources:
Stephan G.
Anagnostaras
University of California, Los Angeles
Department of Neurobiology
Los Angeles, CA 90095-1563
Florence
Crestani
University of Zurich
Winterthurerstrasse 190
8057 Zürich
Switzerland
Hanns Mohler
University of Zurich
Winterthurerstrasse 190
8057 Zürich
Switzerland
From Science
News, Vol. 156, No. 10, September 4, 1999, p. 149. Copyright ©
1999, Science Service. |