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COUGH OVERRIDE
Understanding what brain regions are active when a cough is held back may point to a way to block the urge. The mid insula (a portion of the insular cortex) shows stronger activity when a cough is suppressed than during evoked coughing or normal breathing.

1. Mid insula
2. Cingulate cortex
3. Medulla
4. Pons
5. Cerebellum
6. Midbrain
7. Primary sensorimotor cortex Credit: S.B. Mazzone et al/J. of Neuroscience 2011

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