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STUCK ON STRESS

The glucocorticoid receptor (GR) is key to the body’s stress-response system. In a series of steps involving the HPA axis, stress hormones CRH and ACTH lead to cortisol production. Cortisol communicates with GR to turn off the response. In some people with early life trauma, there is not enough GR to get the “stop” message across.

Source: E.C. Cottrell and J.R. Seckl/Frontiers in Behavioral Neuroscience 2009 Credit: T. Dubé

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  • Is this be the cause of generalized anxiety, panic attacks, etc. to lesser degree than a suicidal response?
    alexa penzner alexa penzner
    Feb. 5, 2013 at 4:18pm
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