Alzheimer's disease appears to particularly affect brain areas involved in the default network. At left, two views of the brain show areas activated (orange) when a healthy person recalls personal memories. Amyloid plaques characteristic of Alzheimer's accumulate (red) and the brain atrophies (blue) in some of the same areas, as shown in scans of people with dementia (middle and right).
Credit: R.L. Buckner et al./Annals NY Academy of Science 2008, reprinted with permission of Blackwell Publishing LTD; M. Raichle (both)
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