Alzheimer's Overlaps Default Network

In the December 5 Issue:

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Climate might be right for a deal: Copenhagen negotiations will take steps toward a climate-stabilizing treaty
Botanical Whales: Adventures in the Tortugas reveal that seagrass fields need saving too
Breaking the Speed Limit: Studies examine physiology and technology to better foresee the ultimate edge of human performance

Alzheimer's overlaps default network

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Alzheimer's disease appears to particularly affect brain areas involved in the default network. At left, two views of the brain show areas activated (orange) when a healthy person recalls personal memories. Amyloid plaques characteristic of Alzheimer's accumulate (red) and the brain atrophies (blue) in some of the same areas, as shown in scans of people with dementia (middle and right).

Credit: R.L. Buckner et al./Annals NY Academy of Science 2008, reprinted with permission of Blackwell Publishing LTD; M. Raichle (both)

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