What leech gut bacteria can tell us about drug resistance | Science News

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What leech gut bacteria can tell us about drug resistance

These microbes were exposed to surprisingly tiny amounts of antibiotics

By
4:35pm, July 24, 2018
leech

BLOODSUCKER  Medicinal leeches like this contain bacteria in their guts that can be transferred to humans. In some cases, it only takes a small exposure to antibiotics for those bacteria to become drug resistant.

Antibiotic resistance in leeches really sucks.

A bacterium found in leeches’ guts needs exposure to only 0.01 micrograms per milliliter of ciprofloxacin to become resistant to that drug, scientists report July 24 in mBio. That’s about 400 times less than the amount of antibiotics thought to trigger drug resistance in this species of bacteria, says study coauthor Joerg Graf, a biologist at the University of Connecticut in Storrs.

Certain leeches are approved for medical use by the U.S. Food and Drug Administration to help patients heal from reconstructive surgery (SN: 10/23/04, p. 266). The slimy creatures suck up blood and secrete anticoagulants, aiding tissue growth.

In the early 2000s, researchers noticed an uptick in antibiotic-resistant infections in these patients that were caused by the Aeromonas

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