SPRINT study results support new, lower target, but also reveal risks of aggressive treatment
fotohunter/Shutterstock; graph: J.T. Wright et al/NEJM 2015
Aggressive treatment for high blood pressure saves lives, newly released data from a recently halted clinical trial suggests.
Using drugs to lower systolic blood pressure to less than 120 millimeters of mercury cut people’s risk of heart attacks and other cardiovascular woes by 25 percent, researchers report November 9 in the New England Journal of Medicine. That’s compared with treatments that aim to drop blood pressure to below 140.
Earlier this year, preliminary results from the trial, named the Systolic Blood Pressure Intervention Trial, or SPRINT, convinced the National Institutes of Health to end the study a year ahead of schedule (SN Online: 9/11/15). At the time, the National Heart, Lung, and Blood Institute