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Drug-resistance gene found—again

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2:34pm, June 28, 2004

Consider it a case of mistaken identity, but one with health implications for hundreds of millions of people. Three years ago, researchers announced they had found a gene that, when mutated, enables the parasite that causes the majority of the world's malaria to shrug off the widely used drug chloroquine (SN: 11/29/97, p. 340: http://www.sciencenews.org/pages/sn_arc97/11_29_97/fob1.htm). It turns out they were wrong.

Thomas E. Wellems of the National Institute of Allergy and Infectious Diseases in Bethesda, Md., and his colleagues can cheerfully admit that fact, however, because they contend they have now captured the right gene.

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