Distinctive personalities in mice related to brain development
Same genes, same environment, different behavior.
Identical twin mice sharing the same mazelike environment develop distinct personalities based on how much they explore their surroundings, researchers report in the May 10 Science. After death, those differences were reflected in the animals’ brains.
The study “highlights something for which we had some intuition before, but actually quantifies it,” says Fred Gage, a neuroscientist at the Salk Institute for Biological Studies in La Jolla, Calif.
Some character and biological differences between identical twins may originate as early as pregnancy. But twins become more and more different as life goes on, even when they grow up together. Scientists have recognized that having distinct experiences within the same environment might boost such personality differences, but that’s difficult to test in humans.
Studying it in animals has multiple benefits. “You can keep the genes