Varying efficacy of HIV drug cocktails explained | Science News


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Varying efficacy of HIV drug cocktails explained

Increasing dose works at critical times in virus’s life cycle

6:07pm, July 13, 2011

A new mathematical model of HIV-fighting drugs reveals the biology beneath the varying success of such treatments. Infection with HIV was a death sentence until the introduction of multidrug cocktails, yet the differential effectiveness of the combinations has remained a puzzle. The research, published July 13 in Science Translational Medicine, could help refine therapies for HIV and other viruses such as hepatitis C.

Slightly boosting the dose of

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