Increasing dose works at critical times in virus’s life cycle
A new mathematical model of HIV-fighting drugs reveals the biology beneath the varying success of such treatments. Infection with HIV was a death sentence until the introduction of multidrug cocktails, yet the differential effectiveness of the combinations has remained a puzzle. The research, published July 13 in Science Translational Medicine, could help refine therapies for HIV and other viruses such as hepatitis C.
Slightly boosting the dose of